Product Description:

Sodium Hyaluronate CAS 9004-61-9, known as Hyaluronic acid, a white or almost white, is a very hygroscopic grain or powder, without odor, turning to clear solution when dissolved in water and insoluble in ethanol. Sodium Hyaluronate is widely used as food addictives, cosmetics material and for the production of pharmaceuticals.

Specifications:

Food grade Sodium Hyaluronate

Appearance                           White powder

pH(0.1% water solution)         6.0-7.5
Molecular weight                    Practical value
Loss on drying                       ≤10.0%
Pesidue on ignition                 ≤13.0%
Heavy metals(as Pb)               ≤20ug/g
Arsenicum                             ≤2ug/g

Glucuronic acid                       ≥42.0%
Bacteria counts                      ≤100CFU/g
Mold&Yeast                           ≤100CFU/g
Escherichia coli                       negative
Staphylococcus aureus            negative

Cosmetic Grade Sodium Hyaluronate

pH(1% water solution)           6.0-7.5
Transparency                        ≥99.0%
Loss on drying                       ≤10.0%
Kinematic viscosity                  Practical value
Molecular weight                    ≥1.00×106
Protein                                 ≤0.1%
Heavy metals(as Pb)               ≤20ug/g
Glucuronic Acid                      ≥44.0%
Sodium Hyaluronate                ≥91.0%
Bacteria counts                      ＜10cfu/g
Mold&Yeast                           ＜10cfu/g
Staphylococcus aureus             negative
Pseudomonas aeruginosa          negative

Pharmaceutical Grade Sodium Hyaluronate

pH(1% water solution)             6.0~7.5
Molecular weight                     (0.8~2.0×106)
Protein                                  ≤0.05%
Loss on drying                         ≤8.0%
Residue on ignition                  ＜15%
Heavy metals(as Pb)                ＜10ug/g
Arsenic                                  ＜2ug/g
Glucuronic Acid                        ≥45.0%
Sterility                                  Complies
Bacterial endotoxin                 ＜1EU/mg

Application:

Food grade Sodium Hyaluronate

HA also plays an important role of water retention and lubrication in other tissues and organs, such as joint cavity, blood vessel, heart and brain. Decrease of HA level of these tissues can result in arthritis, arteriosclerosis, pulse disorder and brain atrophy. Oral HA can restore the normal content of HA in body and delay apolexis and make the body energetic.

At present, HA is widely applied to health and beauty products in the developed countries, such as America, Japan and Europe. It is greatly welcomed by the consumers.

Cosmetic Grade Sodium Hyaluronate

HA is a natural biotic component widely presents in skin and other tissues. It has outstanding moisturizing effect, thus called Natural Moisturizing Factor (NMF) in the world. HA is the best component used in cosmetics for moisturizing from the nature.

When it is applied to skin, macromolecular HA can form a thin layer permeable to air, keeping the skin smooth and moist and further protecting it from bacteria, dust and ultraviolet rays, while micromolecular HA can penetrat into corium, enlarging blood capillaries slightly, promoting blood circulation, improving intermediary metabolism and nourishment-absorbing ability of skin, thus eliminating wrinkles, increasing skin's elasticity and delaying its aging. In addition, HA can further hyperplasia of epidermic cell, clean oxygen-derived free radicals, prevent and rehabilitate skin injuries. Its aqueous solution has very high viscosity which can make water become thicker. Cream made by emulsifying HA with oil is fine and even, homogeneous with stable emulsifiction.

Pharmaceutical Grade Sodium Hyaluronate

HA has unique physicochemical properties and physiological functions. It has been widely applied in the pharmaceutical industry. HA can be used as viscoelastic materials in intraocular lens implantation and as fillers in articular surgery against osteoarthritis, rheumatoid arthritis etc. It is also used as medium in eye drops extensively. Furthermore, HA is helpful in preventing post-surgery conglutination and improving wound healing.